Isolated echogenic foci in the fetal heart as marker of chromosomal abnormality

Fetal Cardiac Echogenic Foci

Departments of Pediatrics and Obstetrics/Gynecology, National Taiwan University Hospital, Taipei, and Department of Pediatrics, Taiwan Provincial Kee-Lung Hospital, Keelung. Received: 15 August 2001. Revised: 11 December 2001. Accepted: 5 February 2002. Reprint requests and correspondence to: Dr. Mei-Hwan Wu, Department of Pediatrics, National Taiwan University Hospital, 7 Chung-Shan South Road...

Fetal echogenic gut: a marker of intrauterine gut ischaemia?

The pathophysiological significance of fetal echogenic gut (FEG) is unknown. Our aim was prospectively to evaluate FEG in infants with intrauterine growth retardation (IUGR) and absent umbilical artery end diastolic flow velocities. Over a 15 month period, nine infants with FEG met these criteria. Nine infants who, on antenatal assessment, had demonstrated IURG and absent umbilical artery end d...

Chromosomal Abnormality in Men with Impaired Spermatogenesis

Congenital Heart Defects and Chromosomal Abnormality

Chromosomal abnormality is one of the causal factors in the formation of the congenital heart defects. 65 patients (33 male and 32 female) with heart defects were referred for karyotyping and counseling. Chromosomal abnormalities were detected in 27 (41.5%) and 38 had a normal karyotype. Numerical abnormality was found in 21 (77.8%) and structural in 6 (22.2%), numerical was detected in 14 fema...

Echogenic intracardiac foci: associated with increased risk for fetal trisomy 21 or not?

OBJECTIVE The purpose of this study was to evaluate the impact of an echogenic intracardiac focus (EIF) on the risk for fetal trisomy 21 (T21) in populations with differing prevalence of T21. METHODS A retrospective cohort study of pregnancies presenting to our prenatal ultrasound units over 16 years (1990-2006) was conducted. Contingency table analysis of the presence of an EIF and diagnosis...